The timing and implant type are also important factors in the implant-prosthetic rehabilitation of cleft lip and palate patients. The highest success rates are found in studies where:
1. a 2-stage procedure was performed with time between augmentation regrafting and implant placement not exceeding 6 months;
2. sufficient bone was present to allow primary stability of the implant;
3. autogenous bone grafts from the iliac crest were used; and
4. implant lengths of at least 13 mm were used in the grafted alveolar site.
Other parameters such as implant surface type may have an influence on the long-term prognosis of the implant, however, the research is limited.
The implementation of implant therapy in combination with alveolar grafts has provided these patients with an effective and viable option to other prosthetic alternatives such as bridges and dentures. Further studies are needed to assess the: long-term success of implants placed in clefts that have received secondary bone grafts; revascularization and resorption of bone grafts; and influence of other implant parameters such as surface characteristics and dimensions on the longevity of this treatment option.